Marked increase in etravirine and saquinavir plasma concentrations during atovaquone/proguanil prophylaxis
نویسندگان
چکیده
منابع مشابه
Etravirine concentrations in seminal plasma in HIV-infected patients.
OBJECTIVES To determine etravirine concentrations and the HIV-1 viral load (VL) in blood plasma (BP) and seminal plasma (SP) of HIV-infected patients. METHODS Ten adult antiretroviral-experienced HIV-1 patients receiving an etravirine-containing regimen for at least 1 month were enrolled. Semen and blood samples were collected ~12 or 24 h after the last etravirine dose, depending on twice-dai...
متن کاملA marked increase in gastric fluid volume during cardiopulmonary bypass
Major physiological stress occurs during cardiac surgery with cardiopulmonary bypass. This is related to hypothermia and artificial organ perfusion. Thus, serious gastrointestinal complications, particularly upper gastrointestinal bleeding, sometimes follow cardiac surgery. We have compared the antisecretory effects of a preanesthetic H(2) antagonist (roxatidine, cardiopulmonary bypass-H(2) gro...
متن کاملMarked decline in atmospheric carbon dioxide concentrations during the Paleogene.
The relation between the partial pressure of atmospheric carbon dioxide (pCO2) and Paleogene climate is poorly resolved. We used stable carbon isotopic values of di-unsaturated alkenones extracted from deep sea cores to reconstruct pCO2 from the middle Eocene to the late Oligocene (approximately 45 to 25 million years ago). Our results demonstrate that pCO2 ranged between 1000 to 1500 parts per...
متن کاملAntiviral prophylaxis during pandemic influenza may increase drug resistance
BACKGROUND Neuraminidase inhibitors (NI) and social distancing play a major role in plans to mitigate future influenza pandemics. METHODS Using the freely available program InfluSim, the authors examine to what extent NI-treatment and prophylaxis promote the occurrence and transmission of a NI resistant strain. RESULTS Under a basic reproduction number of R0 = 2.5, a NI resistant strain can...
متن کاملMarked Increase Chemotherapy in in Plasma ACTH Ectopic ACTH with Tumor Reduction Syndrome
We report on a case of rapid and marked hormone release as a result of rapid tumor reduction due to chemotherapy in a 36-year-old woman with ectopic ACTH syndrome due to small cell lung cancer. Treatment of the cancer with cisplatin and etoposide resulted in an 80% reduction in tumor size on computed tomographic scan within two weeks. Concurrently, plasma ACTH exhibited an unexpected and astoni...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Malaria Journal
سال: 2011
ISSN: 1475-2875
DOI: 10.1186/1475-2875-10-141